seroconversion rates after hepatitis-b vaccination in children

نویسندگان

mandana afsharian

mohammad ghaderi

siavash vaziri

zahra leghaei

چکیده

background: hepatitis- b infection is one of the infectious diseases that transmits via blood transfiosion, blood product, injection, mother to fetus and sexual contact. protective anti hepatitis-b titer are observed in more than 90% of healthy children. the aim of this study was to evaluate seroconversion rates in children who received routine vaccination program. methods: a cross sectional study was designed. 196 children who received routine hepatitis-b vaccine (at birth, 2 and 6 months old) were selected. anti hepatitis-b titer was measured using elisa method in 6-7 years old children. data was analyzed using chi-square and fisher exact tests. results: 69 % of all participants (98 boys and 98 girls) showed protective antibody titer (71.4% in girl and 67% in boys). there was no significant correlation between sex, weight and bmi and antibody response. conclusion: seroconversion rate after hepatitis–b vaccination was lower than the semilar studies. the etiology of low seroconversion rate needs to do further study in kermanshah.

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عنوان ژورنال:
مجله دانشگاه علوم پزشکی کرمانشاه

جلد ۱۵، شماره ۶، صفحات ۰-۰

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